Home > Applications >
Pharmaceutical Product Testing Attachments

Email this page


Any of the texture analyser range can be used for the product tests listed below.

A selection of special attachments and typical measurements are also shown which are commonly used in this application area. However, this does not show the complete range of attachments available for the testing of pharmaceutical products. Test procedures include: compression, puncture/penetration, tension, fracture/bending, extrusion, cutting/shearing.


Typical measurements include:

  • Bloom strength: gelatin gels

  • Gel Strength and Gel-Forming Properties: wound dressings, jelly lubricants, contact lenses, soft gel capsules, suppositories
  • Elasticity & Rupture Force: capsules, breast implants, coronary stents
  • Tablet Strength
  • Swelling and Disintegration: tablets
  • Tablet Coating Adhesion
  • Mucoadhesion
  • Bioadhesion: transdermal patches, films
  • Compressibility: powders, granules, pellets
  • Breaking Strength: bones, artificial limbs, alginate rafts, hard capsules
  • Syringeability: biogels
  • Consistency: creams
  • Adhesiveness: sputum, biogels, dentistry amalgums

Tablet Strength

Gels

Tablet Coating Adhesion Fixture

Tablet Strength
This diametral crush test identifies 
important differences in tablet 
characteristics missed by 
conventional tablet strength 
testers, which only measure the 
point force at which the tablet 
breaks.

Gels
Standard probes such as that 
required for gelatine testing 
(BS 757), as shown above, are 
available for the assessment of 
Bloom strength/Gel strength or 
rupture characteristics of gels.

Tablet Coating 
Adhesion Fixture
This test provides a quantitative 
measure of the adhesion strength 
of the coating to the tablet surface.
Such a test is useful for studying 
the consequences of changes in 
tablet coating formulation variables.

Mucoadhesion Test Rig

Bilayer tablet shear rig

Syringe Testing Rig

Mucoadhesion Test Rig
Tests of solid dosage forms, semi-
solids such as ointments and gels 
and even systems which solidify 
on contact with the target organ 
can be performed.

Bilayer Tablet Shear Rig
(Registered Design)
This rig enables tablet layer
separation to be quantified.

Syringe Testing Rig
(Registered Design)
Allows measurement of the
aspiration and extraction forces
of syringes.

Cylinder probes

Capsule Loop Tensile Rig

Cylinder probes

Cylinder probes
Can be used to assess granule 
compressibility.

Capsule Loop Tensile Rig
(Registered Design)
This rig measures the force
required to split one half of
a hard gel capsule.

Cylinder probes 
(small/large diameter)
Can be used to assess puncture/
compression force of e.g. capsules.

Powder Compaction Rig

Sachet Tube Extrusion Rig

Mini 3 Point Bend Rig

Powder Compaction Rig
(Registered Design)
Allows measurement of the
compaction forces of powders.

Tube/Sachet Extrusion Rig
Allows manufacturers to measure 
the ease of removal and application 
of products such as sauces, pastes,
creams and gels.

Mini 3 Point Bend Rig
Ideally suited to small diameter 
samples such as tablets. Sample 
supports can provide a 2mm 
separation.

Film Support Rig

Acoustic Envelope Detector

Alginate Raft Hook

Film Support Rig
This rig allows testing of thin, film-
like products to measure the burst 
strength, resilience and relaxation 
properties.

Acoustic Emission and 
Video Playback
Allow the collection of acoustic
data during a test and the
synchronisation of force data with
video frames - of particular interest
for the testing of brittle products.

Alginate Raft Hook
(British Pharmacopoeia)
Allows measurement of alginate raft strength.


Application Studies are available for the testing of PHARMACEUTICAL products using the TA.XT2i, TA.XTplus, TA.XTExpress  or TA.HDplus texture analysers.

In addition, scientific papers have been published which reference the use of the TA.XT2i/TA.XTplus/TA.HDplus in the testing of PHARMACEUTICAL products.
Click here for paper titles and citation details.


If you have found this page of interest, and would like to pass the information on,
please click here to notify a colleague


Home  |  Contact us  |  Distributors  |  Texture Analysis  |  Powder Flow Analysis  |  Materials Testing

Copyright © 1996-2009 Stable Micro Systems Ltd. All rights reserved.

 

  TA.XTplus TA.HDplus TA.XT Express